Abbreviations, Acronyms and Definitions
Active Tuberculosis: Tuberculosis is an infection with Mycobacterium tuberculosis. The infection can either be latent, where an individual does not have symptoms and cannot infect others, or progress to active disease, where an individual has symptoms and can spread the bacteria to others (see TB Disease).
AIDS: Acquired immunodeficiency syndrome.
DOT: Directly observed therapy. Healthcare personnel watch patients take their anti-tuberculosis medications to ensure adherence to therapy.
Extrapulmonary TB: A person with Mycobacterium tuberculosis infection outside of the lungs, the pleural space, and the larynx (voice box). A person with extrapulmonary disease can also have pulmonary TB (see below)
HIV: Human immunodeficiency virus, the virus that can lead to AIDS.
IDSS: IDSS stands for Illinois Disease Surveillance System. IDSS is a web-based application that establishes a secure and real-time communication link between hospitals, laboratories and other health care providers with state and local health department staff for the purposes of reporting and managing communicable disease information. All TB cases in suburban Cook County are reported to the Illinois Department of Public Health using IDSS.
INH: Abbreviation for isoniazid, an anti-TB medication.
MDR-TB: Multi drug resistant TB. MDR-TB is defined as TB resistant to isoniazid and rifampin, the two most important first line anti-tuberculosis medications.
National Tuberculosis Indicators Project (NTIP): Monitoring system for tracking the progress of U.S. tuberculosis (TB) control programs toward achieving the national TB program objectives.
Pulmonary TB: A person with Mycobacterium tuberculosis infection of the lungs, pleural space or the larynx (voice box). A person with pulmonary TB can also have extrapulmonary TB.
RIF: Abbreviation for rifampin, an anti-TB medication.
SA: Self-administered therapy. Patients are NOT watched by healthcare personnel while taking their anti-tuberculosis medications.
TB: Tuberculosis.
TB Disease: A person with TB infection who is contagious to others; a person with TB disease can have pulmonary TB, extrapulmonary TB, or both.
XDR-TB: Extensively drug resistant TB. XDR-TB is defined as MDR-TB plus TB that is resistant to any fluoroquinolone plus resistance to one of the three injectable drugs (i.e., amikacin, kanamycin, or capreomycin).
Executive Summary
In suburban Cook County, there were 86 new cases of active TB in 2025. Over the past 5 years, TB rates have increased 62% from 2.1 per 100,000 in 2020 to 3.4 cases per 100,000 in 2025. Nationally, state-wide, and in Chicago, cases have also increased since 2020. The municipalities with the highest number of cases were Skokie, Cicero, Des Plaines, and Hoffman Estates.
The majority of cases (81.4%) were foreign-born, with 3 countries accounting for 51% of the foreign-born cases: India (24%), Mexico (14%), and Philippines (13%). Individuals infected with Mycobacterium tuberculosis can incubate the bacteria for a long time, not realizing that they are infected until they start to feel sick years later. Among foreign-born persons diagnosed with TB, 60.9% arrived in the US 5 or more years prior to receiving a diagnosis of TB disease.
Only 15 US-born TB cases were reported in 2025, but there were notable differences in race/ethnicity depending on whether cases were US- or foreign-born. The majority (73%) of US-born cases identified as White or Black/AA, whereas more foreign-born cases identified as Asian and Hispanic/Latino.
More than 6 out of 10 TB diagnoses in 2025 were 45 years or older, with the largest age group being 65 years and older. There were more male (n=52; 60%) cases than female (n=34; 40%).
In 2025, 56% of cases were tested for drug resistance: Fewer than 5 cases of MDR-TB and no cases of XDR-TB were identified. Of all 2025 cases, 89% were tested for HIV.
Pulmonary TB (either exclusively or in combination with extrapulmonary TB) continued to represent the majority (86%) of active TB cases in suburban Cook County.
CCDPH conducts contact investigations for all pulmonary cases of TB. These contact investigations are the cornerstone of interrupting TB transmission. In 2025, CCDPH investigated 223 contacts to TB cases.
TB Trends By Select Jurisdictions
Figure 1. Trends in TB Diagnoses by Select Public Health Jurisdictions, 2010-2025
- The number of TB diagnoses had declined significantly from 2010-2025 in all selected geographies, but has increased since 2020.
TB in Suburban Cook County
Map 1. 3-Year Average TB Rate per 100,000 Population, Suburban Cook County, 2023-2025
Demographics
Figure 2. Percent of TB Cases by Sex, Suburban Cook County, 2025
- There were more males (n=52; 60%) than females (n=34; 40%) diagnosed with TB in 2025.
Figure 3. Percent of TB Cases by Age Groups, Suburban Cook County, 2025
- More than 6 out of 10 suburban Cook TB cases in 2025 were 45 years or older.
Figure 4. Percent of TB Cases by Place of Birth and Race/Ethnicity, Suburban Cook County, 2025
- There were notable differences in the race/ethnicity distribution depending on whether cases were US- or foreign-born.
Country of Origin
Figure 5. Percent of TB Cases by Place of Birth, Suburban Cook County, 2025
- The vast majority of TB diagnoses in 2025 (81.4%) were in those born overseas.
Figure 6. Percent of TB Cases by Select Countries of Origin and Tenure in the US, Suburban Cook County, 2025
- More than 6 in 10 foreign-born cases diagnosed with TB in 2025 have been living in the US for 5 or more years.
Map 2. Countries of Origin for Suburban Cook County Residents Diagnosed with TB, 2025
Foreign-born people diagnosed with TB in 2025 came from 23 different countries.
In 2025, 51% of newly diagnosed, foreign-born TB cases came from India, Mexico, and Philippines.
Drug Resistance
Figure 7. Drug Resistance in Foreign-born TB Cases in Suburban Cook County, 2025
Figure 8. Drug Resistance in US-born TB Cases in Suburban Cook County, 2025
Pathology
Figure 9. Pulmonary TB Labs, Suburban Cook County, 2025
Includes cases with exclusively pulmonary TB as well as those who have both pulmonary and extrapulmonary TB.
Figure 10. Extrapulmonary TB Labs, Suburban Cook County, 2025
Includes cases with exclusively extrapulmonary TB as well as those who have both pulmonary and extrapulmonary TB.
Figure 11. TB Cases Coinfected with HIV, Suburban Cook County, 2025
Treatment
Figure 13. Trends in Treatment Completion of Antituberculosis Therapy in Pulmonary Cases, Suburban Cook County, 2020-2024
*Includes those alive at the time of diagnosis who started therapy and for whom therapy completion within 1 year was indicated.
The proportion of 2024 eligible TB cases completing therapy in 12 months or fewer in 2024 was 96.5%. This was above the National TB Indicator Project goal of 95%.
The proportion of eligible 2024 TB cases ever completing therapy was 98.2%.
Contacts
Figure 14. Contacts in 2025*
*Data are provisional; evaluations for some contacts may be ongoing.